Make-believe Project Management Database

Problem Description:

My imaginary friend Luke has a fake Project Management Company; he needs me to build a database with a friendly GUI that he can use to keep track of his projects, his clients, and other related information.  
 
System Requirements:

Using this system, the Project Management Company staff should be able to add, delete, or modify all aspects of the underlying database.  The system should be accessible from the internet.  Advanced programming / SQL knowledge should not be necessary for the staff to use the system.  

Business Benefits:

As the backbone of the Project Management Company, this system would have a significant and positive effect on operations; Luke and his staff would be able to efficiently handle more projects, and make more money.